Which of the following signs indicates a potential allergic reaction during medication administration?

Hives, also known as urticaria, are a classic sign of an allergic reaction. This skin manifestation is typically characterized by raised, itchy welts that can vary in size and appear suddenly. When a patient is administered a medication they are sensitive to, the immune system may overreact, resulting in the release of histamine and other chemicals, which causes hives as part of an allergic response.

Recognizing hives during medication administration is crucial, as it can indicate the potential for more severe allergic reactions, such as anaphylaxis. Observing hives or similar skin rashes prompts immediate action, including stopping the medication, notifying the healthcare provider, and monitoring the patient closely for any further symptoms.

While flushing, dry skin, and increased heart rate can be associated with various conditions or medication side effects, they are not definitive signs of an allergic reaction. For example, flushing can occur due to vasodilation or certain drug effects, and increased heart rate might result from anxiety or other non-allergic responses. Dry skin typically represents dermatological issues and does not indicate an allergic response. Therefore, distinguishing hives as a sign of potential allergic reactions is essential for patient safety during medication administration.